Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC210H329N59O76S5

DescriptionStandard

        MEKVLDLDVQVKGNNNTNDSAGDERLTSYSLCSFGCGKTGSFNSFCC
    

Molecular Weight5056.53 Da

Isoelectric Point (pI)4.53

Net Charge (pH 7.0)-2.53

Net Charge (pH 7.4) -2.82

Charge Density (pH 7.0) -0.0539

GRAVY Index-0.39

Hydrophobic Moment 0.40

Boman Index-0.04

Instability Index-2.37

Aliphatic Index 53.83

Aromaticity 0.0851

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2226.52

LogP -31.81

H-bond Donors 80.0

H-bond Acceptors 79.0

Rotatable Bonds 171.0

Heavy Atoms 350.0

Ring Count 4.0

Amide Bonds 52.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0082491 VERIFIED: YES

Provenance & Taxonomy

OrganismStaphylococcus aureus subsp. aureus H19 [Bacterium]

FamilyLantibiotic

Tax ID585155

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

RECORD: Rec_0162309 VERIFIED: NO

Provenance & Taxonomy

OrganismStaphylococcus aureus subsp. aureus D139 [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence

RECORD: Rec_0268720 VERIFIED: NO

Provenance & Taxonomy

OrganismStaphylococcus aureus [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence

RECORD: Rec_0414703 VERIFIED: NO

Provenance & Taxonomy

OrganismStaphylococcus aureus [Bacterium]

FamilyBacteriocin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial