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MYP_022415
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Basic Information
Somatostatin-28
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitory neuropeptide
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Inhibitory neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
28 amino acids
C137H209N41O39S3
Standard
Sequence
SANSNPAMAPRERKAGCKNFFWKTFTSC
Physicochemical Analysis
3150.57 Da
9.85
3.44
3.20
0.1229
-0.73
0.36
-0.16
34.77
14.29
0.1429
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1316.81
-16.58
48.0
46.0
100.0
220.0
7.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0215563 VERIFIED: YES
Provenance & Taxonomy
Macaca fascicularis [Animal]
Somatostatin
9541
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
17-28
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Reproductive regulator
Experimental: 2.8±0.3 minute; /168 seconds; Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Somatostatin-28 (Macaca fascicularis): PMID 2894033##6127205 PMID2894033;6127205 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2894033/
RECORD: Rec_0227232 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Somatostatin
9940
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
17-28
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Reproductive regulator Receptor modulation
Experimental: 2.8±0.3 minute; /168 seconds; Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Somatostatin-28 (Ovis aries): PMID 6109284##6127205 PMID6109284;6127205 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6109284/
RECORD: Rec_0278568 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Somatostatin
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
17-28
Bio-Activity Profile
Hormone Inhibitory neuropeptide
PMID7353633 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7353633/
RECORD: Rec_0314737 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Somatostatin
10116
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
17-28
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Reproductive regulator Receptor modulation
Experimental: 2.8±0.3 minute; /168 seconds; Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Somatostatin-28 (Rattus norvegicus): PMID 6127205 PMID6127205 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6127205/
RECORD: Rec_0361496 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Somatostatin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
17-28
Bio-Activity Profile
Endocrine
Radioimmunoassay
Brodmann Area tissues of brain of SDAT(Alzheimer's Disease Brain Bank, Bronx, NY), in vitro; 13686 s
PMID1346149 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1346149/
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