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MYP_022415
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Basic Information
Somatostatin-28
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitory neuropeptide
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Inhibitory neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
28 amino acids
C137H209N41O39S3
Standard
Sequence
SANSNPAMAPRERKAGCKNFFWKTFTSC
Physicochemical Analysis
3150.57 Da
9.85
3.44
3.20
0.1229
-0.73
0.36
-0.16
34.77
14.29
0.1429
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1316.81
-16.58
48.0
46.0
100.0
220.0
7.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0061156 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 35.7%, E 0.0%, T 32.1%, C 32.1% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication Hormones
PaperHmrbase: a database of hormones and their receptors PMID19589147 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19589147/
RECORD: Rec_0106641 VERIFIED: YES
Provenance & Taxonomy
Macaca fascicularis [Animal]
Somatostatin
9541
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
17-28
Bio-Activity Profile
Hormone Inhibitory neuropeptide
PMID6107906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6107906/
RECORD: Rec_0117588 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Somatostatin
9940
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
17-28
Bio-Activity Profile
Endocrine regulation Neurotransmission modulation Cell proliferation regulation
SS Radioimmunoassay assay
Intravenous infusion in Dog plasma, in vivo; 168 s
PMID6127205 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6127205/
RECORD: Rec_0153615 VERIFIED: YES
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Somatostatin
9615
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
17-28
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Reproductive regulator Receptor modulation
Experimental: 2.8±0.3 minute; /168 seconds; Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Somatostatin-28 (Canis lupus familiaris): PMID 8988514##6127205 PMID8988514;6127205 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8988514/
RECORD: Rec_0155539 VERIFIED: YES
Provenance & Taxonomy
Canis familiaris [Animal]
Somatostatin
9615
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
17-28
Bio-Activity Profile
Hormone Inhibitory neuropeptide
PMID7353633 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7353633/
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