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MYP_022407
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Basic Information
SP12 (De Novo Synthesis)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C76H146N32O15
Standard
Sequence
IRRRIRLIVRRQI
Physicochemical Analysis
1748.18 Da
12.00
5.76
5.56
0.4431
-0.35
0.84
-0.64
149.70
172.31
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
827.01
-6.05
33.0
21.0
63.0
123.0
0.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0054099 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Hemolytic
human blood cells
PaperDe Novo Design and In Vitro Testing of Antimicrobial Peptides against Gram-Negative Bacteria PMID31163671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31163671/
RECORD: Rec_0134963 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Cytotoxic
PaperDe Novo Design and In Vitro Testing of Antimicrobial Peptides against Gram-Negative Bacteria PMID31163671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31163671/
RECORD: Rec_0167525 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Gram-negative bacteria: Escherichia coli ATCC 25922
12.5-25 μg/mL
MIC
PaperDe Novo Design and In Vitro Testing of Antimicrobial Peptides against Gram-Negative Bacteria PMID31163671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31163671/
RECORD: Rec_0202914 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Hemolytic
PaperDe Novo Design and In Vitro Testing of Antimicrobial Peptides against Gram-Negative Bacteria PMID31163671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31163671/
RECORD: Rec_0255156 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
100 μg/mL
Hemolysis
PMID31163671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31163671/
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