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MYP_022387
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Basic Information
TB_KKG6A
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C80H147N19O18
Standard
Sequence
KKLLPIVANLLKSLL
Physicochemical Analysis
1663.14 Da
10.30
2.76
2.55
0.1838
1.05
0.58
0.27
5.19
208.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
603.31
-1.05
20.0
21.0
58.0
117.0
1.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0227003 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis
1.5 μM
MIC
PMID28443279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28443279/
RECORD: Rec_0239981 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
PBMCs
49 μM
IC50
PMID28443279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28443279/
RECORD: Rec_0245266 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans NCPF 3179
3 μM
MIC
PMID30718667;28443280 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30718667/
RECORD: Rec_0259901 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Sheep erythrocytes [No hemolysis observed
Hemolysis
PMID34200504 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34200504/
RECORD: Rec_0262046 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Mouse erythrocytes
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/23403136/ PMID23403136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23403136/
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