Peptide Database

Peptide NameProphenin and tritrpticin precursor (C6) [Cleaved into: Prophenin-1 (PF-1); Tritrpticin]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length212 amino acids

Chemical FormulaC1118H1680N304O278S4

DescriptionStandard

        LLLLALVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTRQPPELCDFKENGRVKQCVGTVTLDQIKDPLDITCNEGVRRFPWWWPFLRRPRLRRQAFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPPFPPPIFPGPWFPPPPPFRPPPFGPPRFPGRR
    

Molecular Weight23955.43 Da

Isoelectric Point (pI)10.38

Net Charge (pH 7.0)10.75

Net Charge (pH 7.4) 10.45

Charge Density (pH 7.0) 0.0507

GRAVY Index-0.66

Hydrophobic Moment 0.77

Boman Index-0.06

Instability Index65.51

Aliphatic Index 57.45

Aromaticity 0.1179

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049235 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyCathelicidin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria