Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC474H783N121O133S8

DescriptionStandard

        MKLFLILIILLFEVSEDAARSRKCFSTIAGYCKKKCMLGEIYDKPCTKGKLCCINESKKKTHQQAVQQPEPASKPDLKLDYVILPTVTLGTIPQ
    

Molecular Weight10561.54 Da

Isoelectric Point (pI)9.08

Net Charge (pH 7.0)5.53

Net Charge (pH 7.4) 5.14

Charge Density (pH 7.0) 0.0588

GRAVY Index-0.08

Hydrophobic Moment 0.57

Boman Index0.02

Instability Index43.26

Aliphatic Index 96.49

Aromaticity 0.0638

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4085.08

LogP -32.85

H-bond Donors 144.0

H-bond Acceptors 148.0

Rotatable Bonds 360.0

Heavy Atoms 736.0

Ring Count 13.0

Amide Bonds 99.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0208874 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus [Animal]

FamilyDefensin

Tax ID30521

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence