Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC539H874N146O165S3

DescriptionStandard

        PDLTGREKFGLGNVKYNISSIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRGTVHISKVFVTAIFSTPLDNAGPTSISLTSCRTTSGDIEIKLNGKS
    

Molecular Weight12135.78 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)3.13

Net Charge (pH 7.4) 2.94

Charge Density (pH 7.0) 0.0274

GRAVY Index0.07

Hydrophobic Moment 0.54

Boman Index0.13

Instability Index26.36

Aliphatic Index 97.46

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4967.39

LogP -56.86

H-bond Donors 177.0

H-bond Acceptors 173.0

Rotatable Bonds 402.0

Heavy Atoms 853.0

Ring Count 16.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0392992 VERIFIED: NO

Provenance & Taxonomy

OrganismPomatostomus ruficeps [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria