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MYP_022312
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
7 amino acids
C40H67N9O8
Standard
Sequence
LHLPLPL
Physicochemical Analysis
802.02 Da
6.74
-0.15
-0.41
-0.0218
1.26
0.16
0.58
63.60
222.86
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
249.02
1.47
7.0
9.0
21.0
57.0
3.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0267380 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
ACE-inhibitory peptide
9925
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperAngiotensin I-converting enzyme inhibitory activity of enzymatic hydrolysates of goat milk protein fractions
RECORD: Rec_0280801 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperMiguel M., Recio I., Ramos M., Delgado M. A., Aleixandre M. A.. Antihypertensive effect of peptides obtained from Enterococcus faecalis-fermented milk in rats. J. Dairy Sci., 89, 3352-3359, 2006.
RECORD: Rec_0292367 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
432.7 μM
IC50
PaperAntihypertensive effect of peptides obtained from Enterococcus faecalis-fermented milk in rats. PMID16899668 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16899668/
RECORD: Rec_0326603 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Spontaneously hypertensive rats (SHR)
425±44 μM
IC50
PaperIdentification of novel antihypertensive peptides in Milk fermented with Enterococcus faecalis
RECORD: Rec_0326921 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
34.2 μg/mL
IC50
PaperEnterococcus faecalis strains from food, environmental, and clinical origin produce ACE-inhibitory peptides and other bioactive peptides during growth in bovine skim milk PMID23845432 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23845432/
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