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MYP_022294
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Basic Information
WW307
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
8 amino acids
C67H87N21O9
Standard
Sequence
RRRWWWWV
Physicochemical Analysis
1330.54 Da
12.00
2.76
2.56
0.3450
-1.61
0.34
-0.41
212.94
36.25
0.5000
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
515.88
1.13
22.0
12.0
36.0
97.0
8.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0155986 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Toxicity
HepaRG
>80 μM
LC50
Human 15 min
PaperTwo distinct amphipathic peptide antibiotics with systemic efficacy PMID32723829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32723829/
RECORD: Rec_0176916 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Toxicity
mouse splenocytes
>12.5 μM
LC50
Human 15 min
PaperTwo distinct amphipathic peptide antibiotics with systemic efficacy PMID32723829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32723829/
RECORD: Rec_0188584 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Gram+ and Gram- pathogens, E. faecium V286-17
2 μM
MIC
Human 15 min
PaperTwo distinct amphipathic peptide antibiotics with systemic efficacy PMID32723829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32723829/
RECORD: Rec_0234222 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli C3
4 μg/mL
MIC
PMID33804947 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33804947/
RECORD: Rec_0249223 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli G92
4 μg/mL
MIC
PMID33804947 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33804947/
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