Peptide Database

Peptide NameThymosin alpha-1

Function Ontology

Anticancer

Antiviral

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2

Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HBV

Antiviral ▸ Antiviral adjunct

Antiviral ▸ Antiviral support

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Immunomodulation ▸ Immunogen

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC127H213N33O54

DescriptionStandard

        SDAAVDTSSEITTKDLKEKKEVVEEAEN
    

Molecular Weight3066.24 Da

Isoelectric Point (pI)4.25

Net Charge (pH 7.0)-5.52

Net Charge (pH 7.4) -5.75

Charge Density (pH 7.0) -0.1973

GRAVY Index-1.03

Hydrophobic Moment 0.40

Boman Index-0.25

Instability Index28.15

Aliphatic Index 69.64

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1453.27

LogP -18.27

H-bond Donors 49.0

H-bond Acceptors 49.0

Rotatable Bonds 110.0

Heavy Atoms 214.0

Ring Count 0.0

Amide Bonds 28.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0293906 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyThymosin alpha 1 analog

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

Bio-Activity Profile

Function

Immunomodulatory Antiviral support

Half-LifeApprox. 2 h

PaperPubMed-linked source references: PMID:18020580; PMID:17600289; PMID:16307501; PMID:15813890; PMID:15641208; PMID:15641207; PMID:15546254; PMID:15546253; PMID:15482167 PMID18020580;17600289;16307501;15813890;15641208;15641207;15546254;15546253;15482167 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18020580/

RECORD: Rec_0298172 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyThymosin alpha-1

Tax ID9606

Structure & Mods

Configbranched peptide architecture [Branched]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

Other ModsNα-acetylated therapeutic form

Bio-Activity Profile

Function

Antiviral Anti-HBV Immunomodulatory

TargetHepatitis B virus

RECORD: Rec_0426020 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Mus musculus [Animal]; Bos taurus [Animal]

FamilyInterferon

Tax ID9606;10090;9913

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Anticancer Immunomodulatory Hormone replacement Vaccine Immunogen

Half-LifeApprox. 2 hrs

FIRST PREV 1 2

Showing 3 records on this page Ã‚Â· Page 2 of 2