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MYP_022259
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Basic Information
pNP-43c
Anticancer
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
not Standard
6 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
FXTXVF
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007855 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
D-Orn; D-Dab; D-Phe; head-to-tail cyclization
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID34699170 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34699170/
RECORD: Rec_0432627 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
Mixed
D-Orn; D-Dab; D-Phe; head-to-tail cyclization
Bio-Activity Profile
Antiprotozoal Anti-amoebic
Balamuthia mandrillaris
10.04±0.16 μM
IC50
PaperCyclic Peptide Natural Product Inspired Inhibitors of the Free-Living Amoeba Balamuthia mandrillaris PMID39948695
RECORD: Rec_0432628 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
Mixed
D-Orn; D-Dab; D-Phe; head-to-tail cyclization
Bio-Activity Profile
Antiprotozoal Anti-amoebic
Balamuthia mandrillaris
11.23±0.22 μM
IC90
PaperCyclic Peptide Natural Product Inspired Inhibitors of the Free-Living Amoeba Balamuthia mandrillaris PMID39948695
RECORD: Rec_0432629 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
Mixed
D-Orn; D-Dab; D-Phe; head-to-tail cyclization
Bio-Activity Profile
Antiprotozoal Anti-amoebic
Acanthamoeba castellanii
12.6 μg/mL
IC50
PaperCyclic Peptide Natural Product Inspired Inhibitors of the Free-Living Amoeba Balamuthia mandrillaris PMID39948695
RECORD: Rec_0432630 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
Mixed
D-Orn; D-Dab; D-Phe; head-to-tail cyclization
Bio-Activity Profile
Antiprotozoal Anti-amoebic
Acanthamoeba castellanii
>16 μg/mL
IC90
PaperCyclic Peptide Natural Product Inspired Inhibitors of the Free-Living Amoeba Balamuthia mandrillaris PMID39948695
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