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MYP_022244
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Basic Information
Sub3 (Bac2A variant through three amino acids substitution)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Standard
12 amino acids
C74H133N31O13
Standard
Sequence
RRWRIVVIRVRR
Physicochemical Analysis
1665.05 Da
12.00
5.76
5.56
0.4800
-0.53
0.46
-0.70
145.29
137.50
0.0833
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
770.61
-4.91
32.0
19.0
56.0
118.0
2.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0338653 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
methicillin-resistant Staphylococcus aureus
2 μg/mL
MIC
PMID31616307 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31616307/
RECORD: Rec_0341387 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
S. enterica ssp. Typhimurium or Salmonella Typhimurium
4 μM
MIC
PaperHigh-throughput generation of small antibacterial peptides with improved activity PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
RECORD: Rec_0342622 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa
2 μg/mL
MIC
25% aqueous mouse serum, in vitro; ~3600 s
PMID20585128 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20585128/
RECORD: Rec_0354464 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis ATCC 29212
4 μg/mL
MIC
PMID31616307 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31616307/
RECORD: Rec_0357024 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic designed peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis strain H37Rv
MIC
PMID23141114 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23141114/
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