Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length52 amino acids

Chemical FormulaC240H405N63O79S6

DescriptionStandard

        MKMNEVALTALDEVSELELNDILGAKGKGSGVIKTLTHECKMNTYQAILTCC
    

Molecular Weight5629.55 Da

Isoelectric Point (pI)5.09

Net Charge (pH 7.0)-2.43

Net Charge (pH 7.4) -2.76

Charge Density (pH 7.0) -0.0468

GRAVY Index0.07

Hydrophobic Moment 0.46

Boman Index0.10

Instability Index32.11

Aliphatic Index 99.42

Aromaticity 0.0192

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2301.50

LogP -23.18

H-bond Donors 81.0

H-bond Acceptors 84.0

Rotatable Bonds 197.0

Heavy Atoms 388.0

Ring Count 2.0

Amide Bonds 55.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0359755 VERIFIED: NO

Provenance & Taxonomy

OrganismPeriweissella cryptocerci [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear lantibiotic precursor [Linear]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLantibiotic-family precursor annotation suggests post-translational lanthionine/methyllanthionine thioether crosslinks in the mature peptide

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria

MethodQualitative functional evidence