Peptide Database

Peptide Namehuman defensin 5

Function Ontology

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Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC153H248N50O44S6

DescriptionStandard

        STCYCRIGLCAAIESYSGRCYISGRRYRLCCR
    

Molecular Weight3684.30 Da

Isoelectric Point (pI)9.15

Net Charge (pH 7.0)4.40

Net Charge (pH 7.4) 4.10

Charge Density (pH 7.0) 0.1375

GRAVY Index-0.03

Hydrophobic Moment 0.46

Boman Index-0.16

Instability Index39.70

Aliphatic Index 67.19

Aromaticity 0.1250

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1556.19

LogP -18.24

H-bond Donors 67.0

H-bond Acceptors 55.0

Rotatable Bonds 119.0

Heavy Atoms 253.0

Ring Count 4.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0170484 VERIFIED: YES

Provenance & Taxonomy

OrganismPongo abelii [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)