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MYP_022201
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Basic Information
A2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
14 amino acids
C84H164N28O15
Standard
Sequence
KRKLILKRILIKRK
Physicochemical Analysis
1806.38 Da
12.00
7.76
7.54
0.5539
-0.58
0.12
-0.56
88.46
167.14
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
757.42
-2.59
29.0
23.0
71.0
127.0
0.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0070236 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperRational design of artificial beta-strand-forming antimicrobial peptides with biocompatible properties. Mol Pharm. 2014 Oct 6;11(10):3492-3502. doi: 10.1021/mp500271c. PMID: 25192319. PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
RECORD: Rec_0174053 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human histiocytic lymphoma U-937
64 μM
LD50
PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
RECORD: Rec_0185375 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperRational design of artificial beta-strand-forming antimicrobial peptides with biocompatible properties. Mol Pharm. 2014 Oct 6;11(10):3492-3502. doi: 10.1021/mp500271c. PMID: 25192319. PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
RECORD: Rec_0240630 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: U-937
64 μM
LD50
PaperRational design of artificial beta-strand-forming antimicrobial peptides with biocompatible properties. Mol Pharm. 2014 Oct 6;11(10):3492-3502. doi: 10.1021/mp500271c. PMID: 25192319. PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
RECORD: Rec_0303223 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus xylosus
8 μM
MIC
PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
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