Peptide Database

Peptide NameOpistoporin-4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC314H486N80O90S2

DescriptionStandard

        GKVWDWIKKTAKDVLNSDVAKQLKNKALNAAKNFVAEKIGATPSEAGQMPFDEFMDILHYY
    

Molecular Weight6885.83 Da

Isoelectric Point (pI)8.20

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.57

Charge Density (pH 7.0) 0.0139

GRAVY Index-0.44

Hydrophobic Moment 0.72

Boman Index0.01

Instability Index37.86

Aliphatic Index 76.89

Aromaticity 0.1148

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2764.50

LogP -22.05

H-bond Donors 92.0

H-bond Acceptors 94.0

Rotatable Bonds 232.0

Heavy Atoms 486.0

Ring Count 12.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0324654 VERIFIED: NO

Provenance & Taxonomy

OrganismOpistophthalmus carinatus [Animal]

FamilyNon-disulfide-bridged peptide (NDBP) superfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Antifungal Fungicide Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence