Peptide Database

Peptide NameDEFB130A isoform 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length79 amino acids

Chemical FormulaC400H657N105O105S7

DescriptionStandard

        MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEEKKCCRRWWIFEPYPTPVPKGKSP
    

Molecular Weight8841.59 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)6.53

Net Charge (pH 7.4) 6.15

Charge Density (pH 7.0) 0.0826

GRAVY Index0.01

Hydrophobic Moment 0.60

Boman Index0.05

Instability Index29.45

Aliphatic Index 98.61

Aromaticity 0.0633

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3333.12

LogP -24.86

H-bond Donors 120.0

H-bond Acceptors 120.0

Rotatable Bonds 292.0

Heavy Atoms 617.0

Ring Count 15.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010396 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Animal]

Tax ID9601

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal