Peptide Database

Peptide NameMtDef5A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC241H373N75O66S8

DescriptionStandard

        KLCQKRSTTWSGPCLNTGNCKRQCINVEHATFGACHRQGFGFACFCYKKC
    

Molecular Weight5633.52 Da

Isoelectric Point (pI)9.25

Net Charge (pH 7.0)6.85

Net Charge (pH 7.4) 6.42

Charge Density (pH 7.0) 0.1370

GRAVY Index-0.42

Hydrophobic Moment 0.35

Boman Index-0.10

Instability Index51.64

Aliphatic Index 35.20

Aromaticity 0.1200

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2306.83

LogP -28.09

H-bond Donors 89.0

H-bond Acceptors 83.0

Rotatable Bonds 185.0

Heavy Atoms 390.0

Ring Count 10.0

Amide Bonds 55.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0014779 VERIFIED: YES

Provenance & Taxonomy

OrganismMedicago truncatula [Plant]

FamilyDefensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidemultiple disulfide bonds reported, sites not specified

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive

TargetClavibacter michiganensis

Activity12 μM

MethodMIC

RECORD: Rec_0101141 VERIFIED: YES

Provenance & Taxonomy

OrganismMedicago truncatula [Plant]

FamilyDefensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidemultiple disulfide bonds reported, sites not specified

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-negative

TargetXanthomonas campestris

Activity12 μM

MethodMIC

RECORD: Rec_0333519 VERIFIED: YES

Provenance & Taxonomy

OrganismMedicago truncatula [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetClavibacter michiganensis subsp. Nebraskensis strain CIC 395

Activity12 μM

MethodMIC

RECORD: Rec_0384756 VERIFIED: YES

Provenance & Taxonomy

OrganismMedicago truncatula [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetXanthomonas campestris pv. campestris 8004

Activity12 μM

MethodMIC