Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length177 amino acids

Chemical FormulaC853H1363N255O248S10

DescriptionStandard

        MNTKIKYGLSAAVLALIAAGASAPEILDQFLDEKEGNHTTAYRDGAGIWTICRGATRVDGKPVIPGMKLSKGKCDRVNAIERDKALAWVEKNIKVPLTEPQKAGIASFCPYNIGPGKCFPSTFYKRINAGDRRGACEALRWWIKDGGRDCRIRSNNCYGQVSRRDQESALACWGIDR
    

Molecular Weight19479.16 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)9.52

Net Charge (pH 7.4) 9.09

Charge Density (pH 7.0) 0.0538

GRAVY Index-0.42

Hydrophobic Moment 0.73

Boman Index-0.08

Instability Index40.82

Aliphatic Index 75.65

Aromaticity 0.0791

Extinction Coeff. Reduced 34950.00

Extinction Coeff. Oxidized 35450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8145.39

LogP -88.28

H-bond Donors 294.0

H-bond Acceptors 269.0

Rotatable Bonds 649.0

Heavy Atoms 1366.0

Ring Count 28.0

Amide Bonds 188.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0180905 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyLysozyme

Tax ID585034

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence