Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length203 amino acids

Chemical FormulaC968H1493N237O283S10

DescriptionStandard

        ECTWEMPSEGPMELVTAKIDAMAGIDYSLVAPPAATAQSLDVDLKGEFFSLAHRSAVPFPPLALALPPDHDRMVYFGASSYFFNTASVAYHAAGALVLDITNSIPKDVEFHLNTSTFSAFVPQVSAWPCLPIMKVRLSTPSAPFLTIGPDGLSLRPVVDIQTYAILPNSTLAPLFLLSLVSCDCGSVGAAQGAPTASAAAVCP
    

Molecular Weight21299.28 Da

Isoelectric Point (pI)4.58

Net Charge (pH 7.0)-8.85

Net Charge (pH 7.4) -9.32

Charge Density (pH 7.0) -0.0436

GRAVY Index0.43

Hydrophobic Moment 0.57

Boman Index0.27

Instability Index39.45

Aliphatic Index 94.78

Aromaticity 0.0887

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18700.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0061376 VERIFIED: NO

Provenance & Taxonomy

OrganismMelopsittacus undulatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence