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MYP_021993
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Basic Information
Indolicidin [W4L,W6L,W8L,W9L,W11L]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C75H136N20O14
Standard
Sequence
ILPLKLPLLPLRR
Physicochemical Analysis
1542.01 Da
12.00
2.76
2.55
0.2122
0.74
0.45
0.12
114.31
210.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
535.97
0.71
18.0
17.0
48.0
109.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0285920 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 46.2%, C 53.8% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0287253 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
50 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/20196123/ PMID20196123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20196123/
RECORD: Rec_0332996 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli IFO 12734
25 μg/mL
MIC
PMID11695650;20196123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11695650/
RECORD: Rec_0345812 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
100 % hemolysis at 50 μM
Hemolysis
PMID11695650;20196123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11695650/
RECORD: Rec_0406884 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis IFO 3513
6.25 μg/mL
MIC
PMID11695650;20196123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11695650/
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