Peptide Database

Peptide NameInsulin B chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC149H221N39O44S2

DescriptionStandard

        AASQHLCGSHLVEALFLVCGESGFFYNPNKS
    

Molecular Weight3326.71 Da

Isoelectric Point (pI)6.01

Net Charge (pH 7.0)-1.05

Net Charge (pH 7.4) -1.37

Charge Density (pH 7.0) -0.0337

GRAVY Index0.24

Hydrophobic Moment 0.29

Boman Index0.24

Instability Index36.90

Aliphatic Index 78.71

Aromaticity 0.1290

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1315.93

LogP -13.79

H-bond Donors 46.0

H-bond Acceptors 47.0

Rotatable Bonds 105.0

Heavy Atoms 234.0

Ring Count 7.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0006203 VERIFIED: YES

Provenance & Taxonomy

OrganismAmia calva [Animal]

FamilyInsulin

Tax ID7924

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour