Peptide Database

Peptide NameSLAY-screened peptide P2299

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC26H38N6O9

DescriptionStandard

        AQPYT
    

Molecular Weight578.61 Da

Isoelectric Point (pI)5.57

Net Charge (pH 7.0)-0.21

Net Charge (pH 7.4) -0.39

Charge Density (pH 7.0) -0.0410

GRAVY Index-1.06

Hydrophobic Moment 0.27

Boman Index0.02

Instability Index29.54

Aliphatic Index 20.00

Aromaticity 0.2000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 254.48

LogP -2.54

H-bond Donors 8.0

H-bond Acceptors 9.0

Rotatable Bonds 14.0

Heavy Atoms 41.0

Ring Count 2.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0291058 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/