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MYP_021901
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Basic Information
Unnamed
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
35 amino acids
C161H258N46O59
Standard
Sequence
FNVALDQVFESIENSQALVDQSNRILSSAEKGNTG
Physicochemical Analysis
3782.04 Da
4.18
-3.23
-3.44
-0.0923
-0.34
0.60
-0.01
40.68
89.14
0.0571
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1750.15
-23.54
58.0
56.0
130.0
266.0
2.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0068824 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 71.4%, E 0.0%, T 8.6%, C 20.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0102587 VERIFIED: YES
Provenance & Taxonomy
Human metapneumovirus [Virus]
Virus-derived peptide
162145;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor Fusion inhibitor
Human metapneumovirus (Virus entry); LLC-MK2
1.52 μM
RT-PCR
PaperIdentification and evaluation of a highly effective fusion inhibitor for human metapneumovirus. | Deffrasnes C, Hamelin ME, Prince GA, Boivin G. | Antimicrob Agents Chemother. 2008 | PMID:17967906 PMID17967906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17967906/
RECORD: Rec_0102907 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 17967906 PMID17967906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17967906/
RECORD: Rec_0121333 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
LLC-MK2 cells at the highest concentrations tested (9 μM)
PaperPubMed PMID: 17967906 PMID17967906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17967906/
RECORD: Rec_0177643 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Human Metapneumovirus(hMPV):inhibition of viral infection in LLC-MK2 cells
1.52 μM
IC50
PaperPubMed PMID: 17967906 PMID17967906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17967906/
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