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MYP_021899
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Basic Information
Proline-rich Peptide 5
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
13 amino acids
C65H96N16O21
Standard
Sequence
SPPSEQLGKSFNF
Physicochemical Analysis
1437.55 Da
5.72
-0.54
-0.75
-0.0414
-0.85
0.44
-0.02
84.20
30.00
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
605.13
-7.50
19.0
21.0
44.0
102.0
4.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0193836 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0213397 VERIFIED: YES
Provenance & Taxonomy
Marine snail [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-negative bacterium: Klebsiella pneumoniae
PMID21703315 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21703315/
RECORD: Rec_0236297 VERIFIED: YES
Provenance & Taxonomy
Rapana venosa [Animal]
Peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperPeptides. 2011 Jul;32(7):1477-83 | http://www.ncbi.nlm.nih.gov/pubmed/21703315 PMID21703315 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21703315/
RECORD: Rec_0265753 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 30.8%, E 0.0%, T 30.8%, C 38.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0371026 VERIFIED: YES
Provenance & Taxonomy
Marine snail [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID21703315 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21703315/
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