Peptide Database

Peptide Name[T24A]GexIVA[1,2]

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC138H229N55O40S4

DescriptionStandard

        TCRSSGRYCRSPYDRRRRYCRRIADACV
    

Molecular Weight3426.90 Da

Isoelectric Point (pI)10.31

Net Charge (pH 7.0)6.36

Net Charge (pH 7.4) 6.10

Charge Density (pH 7.0) 0.2271

GRAVY Index-1.22

Hydrophobic Moment 0.83

Boman Index-0.68

Instability Index155.78

Aliphatic Index 31.43

Aromaticity 0.1071

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1613.54

LogP -21.39

H-bond Donors 68.0

H-bond Acceptors 51.0

Rotatable Bonds 111.0

Heavy Atoms 237.0

Ring Count 4.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0071564 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyConotoxin

Tax ID32630

Structure & Mods

Configdisulfide-constrained linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-9; 20-27

Bio-Activity Profile

Function

Analgesic

Targetα9α10 nicotinic acetylcholine receptor

RECORD: Rec_0335562 VERIFIED: YES