Peptide Database

Peptide NameBeta-defensin 14 (BD-14) (Defensin; beta 14)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC350H574N106O82S7

DescriptionStandard

        MRLHYLLFVFLILFLVPAPGDTFIPKSLRRFFCRVRGGRCAILNCLGKEEQIGRCSNRGQKCCRKKK
    

Molecular Weight7803.42 Da

Isoelectric Point (pI)10.40

Net Charge (pH 7.0)11.53

Net Charge (pH 7.4) 11.16

Charge Density (pH 7.0) 0.1721

GRAVY Index-0.00

Hydrophobic Moment 0.82

Boman Index-0.08

Instability Index48.47

Aliphatic Index 91.64

Aromaticity 0.1045

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3064.63

LogP -23.99

H-bond Donors 116.0

H-bond Acceptors 102.0

Rotatable Bonds 265.0

Heavy Atoms 545.0

Ring Count 11.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0136338 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10116

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic