Peptide Database

Peptide NameSLAY-screened peptide P780

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC86H134N24O29S

DescriptionStandard

        AFTPSVKNPSPANGAPNDCI
    

Molecular Weight2000.19 Da

Isoelectric Point (pI)5.87

Net Charge (pH 7.0)-0.21

Net Charge (pH 7.4) -0.42

Charge Density (pH 7.0) -0.0107

GRAVY Index-0.38

Hydrophobic Moment 0.31

Boman Index0.08

Instability Index55.35

Aliphatic Index 49.00

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 834.34

LogP -12.20

H-bond Donors 26.0

H-bond Acceptors 30.0

Rotatable Bonds 56.0

Heavy Atoms 140.0

Ring Count 5.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0115414 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/