MYP_021778
Lebetin-2-beta
Cardiovascular
Enzyme modulation
▸
Enzyme inhibition
▸
ACE inhibition
▸
ACE inhibitory
Enzyme modulation
▸
Enzyme inhibition
▸
Cell Aggregation Inhibitor
Hormonal / Endocrine
▸
Hormone peptide
Standard
37 amino acids
C164H264N54O52S2
Standard
DNKPPKKGPPNGCFGHKIDRIGSHSGLGCNKVDDNKG
3888.31 Da
9.19
2.91
2.57
0.0787
-1.31
0.65
-0.24
24.36
39.46
0.0270
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1713.16
-23.45
57.0
59.0
130.0
272.0
7.0
40.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0005645
VERIFIED: YES
Provenance & Taxonomy
Macrovipera lebetinus [Animal]
Lebetin-2
3148341
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
13-29
Bio-Activity Profile
Hormone
Endocrine
Cardiovascular
ACE inhibitory
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
RECORD: Rec_0022626
VERIFIED: YES
Provenance & Taxonomy
Macrovipera lebetinus [Animal]
Lebetin-2
3148341
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
13-29
Bio-Activity Profile
Hormone
Endocrine
Cardiovascular
ACE inhibitory
0.14 μM
IC50
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
RECORD: Rec_0195197
VERIFIED: NO
Provenance & Taxonomy
Vipera lebetina [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
13-29
Bio-Activity Profile
Cell Aggregation Inhibitor