Peptide Database

Peptide NameAlyteserin-2a [A9W]

Function Ontology

Anticancer

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC80H135N19O21

DescriptionStandard

        ILGKLLSTWAGLLSNL
    

Molecular Weight1699.04 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0474

GRAVY Index1.11

Hydrophobic Moment 0.42

Boman Index0.47

Instability Index-7.99

Aliphatic Index 176.88

Aromaticity 0.0625

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 645.41

LogP -3.63

H-bond Donors 23.0

H-bond Acceptors 22.0

Rotatable Bonds 56.0

Heavy Atoms 120.0

Ring Count 2.0

Amide Bonds 16.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0056630 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAlyteserin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

RECORD: Rec_0139036 VERIFIED: YES

Provenance & Taxonomy

OrganismAlytes obstetricans [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Cell-penetrating peptide

Targethuman erythrocytes

Activity39 μM

MethodLC50

RECORD: Rec_0309492 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAlyteserin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetTumor cells: A549

Activity21 μM

MethodLC50

RECORD: Rec_0331692 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAlyteserin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

Targethuman erythrocytes

Activity39 μM

MethodHemolysis

RECORD: Rec_0376294 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Toxic Drug Delivery Vehicle Cell-penetrating peptide Hemolytic