Peptide Database

Peptide NameE30

Function Ontology

Antimicrobial

Antiparasitic ▸ Antimalarial

Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC137H215N39O40

DescriptionStandard

        NPPDHSAPLGATRPSAPPLPHVVDLPQLGP
    

Molecular Weight3048.41 Da

Isoelectric Point (pI)5.98

Net Charge (pH 7.0)-1.06

Net Charge (pH 7.4) -1.37

Charge Density (pH 7.0) -0.0354

GRAVY Index-0.45

Hydrophobic Moment 0.39

Boman Index0.10

Instability Index56.13

Aliphatic Index 81.33

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1168.84

LogP -12.52

H-bond Donors 34.0

H-bond Acceptors 41.0

Rotatable Bonds 80.0

Heavy Atoms 216.0

Ring Count 11.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0315051 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyE30

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Antimalarial

TargetPlasmodium falciparum 3D7

Activity>40 μM

MethodIC50; Fluorimetry (SYBR Green I)

RECORD: Rec_0325952 VERIFIED: YES