Peptide Database

Peptide NameMaculatin 1.2

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC109H167N31O29

DescriptionStandard

        GLFVGLAKVAAHNNPAIAEHFQA
    

Molecular Weight2375.68 Da

Isoelectric Point (pI)6.92

Net Charge (pH 7.0)-0.06

Net Charge (pH 7.4) -0.37

Charge Density (pH 7.0) -0.0028

GRAVY Index0.44

Hydrophobic Moment 0.34

Boman Index0.32

Instability Index8.12

Aliphatic Index 102.17

Aromaticity 0.0870

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 944.68

LogP -8.17

H-bond Donors 30.0

H-bond Acceptors 31.0

Rotatable Bonds 74.0

Heavy Atoms 169.0

Ring Count 5.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0401040 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria genimaculate [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other ModsStreptococcus uberis is recognized around the world as the problem mastitis bug. This peptide appears to be particularly effective in eliminating this bug. Chemical modification: C-terminal NH2. A=26%

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetStreptococcus uberis

Activity6 μg/mL

MethodMIC

RECORD: Rec_0417758 VERIFIED: YES