Peptide Database

Peptide NameDisruptin gp28

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length56 amino acids

Chemical FormulaC276H459N79O75S

DescriptionStandard

        MSKFKKYLGAAWDFTKEHGVTILRGVAVLLVGRKVGRVANQSADVLDTVIKGTKKN
    

Molecular Weight6116.15 Da

Isoelectric Point (pI)10.29

Net Charge (pH 7.0)6.58

Net Charge (pH 7.4) 6.30

Charge Density (pH 7.0) 0.1176

GRAVY Index-0.06

Hydrophobic Moment 0.84

Boman Index0.01

Instability Index5.97

Aliphatic Index 99.11

Aromaticity 0.0714

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2522.23

LogP -22.97

H-bond Donors 90.0

H-bond Acceptors 84.0

Rotatable Bonds 212.0

Heavy Atoms 431.0

Ring Count 6.0

Amide Bonds 58.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0295632 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage phiKT [Virus]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Cytolytic Non-hemolytic Non-ribosomal

MethodQualitative functional evidence