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MYP_021718
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Basic Information
NRC-12
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C135H208N38O31
Standard
Sequence
GWKKWFNRAKKVGKTVGGLAVDHYL
Physicochemical Analysis
2859.33 Da
10.30
4.84
4.58
0.1937
-0.52
0.72
-0.02
17.45
74.00
0.1600
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1134.83
-7.10
41.0
37.0
95.0
204.0
7.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0302368 VERIFIED: YES
Provenance & Taxonomy
American plaice [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
C-terminal NH2
Bio-Activity Profile
Antimicrobial Antifungal
C623
16 μM
MIC
PaperNovel antimicrobial peptides derived from flatfish genes PMID12878506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878506/
RECORD: Rec_0302811 VERIFIED: YES
Provenance & Taxonomy
American plaice [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
C-terminal NH2
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli CGSC4908
2 μM
MIC
PaperNovel antimicrobial peptides derived from flatfish genes PMID12878506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878506/
RECORD: Rec_0315648 VERIFIED: YES
Provenance & Taxonomy
Hippoglossoides platessoides [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli CGSC4908
2 μg/mL
MIC
PaperPatenting computer-designed peptides. Journal of Computer-Aided Molecular Design, 12: 543-556 Evidence URLhttps://camp3.bicnirrh.res.in/seqDisp.php?id=CAMPSQ2884
RECORD: Rec_0316333 VERIFIED: YES
Provenance & Taxonomy
American plaice [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
C-terminal NH2
Bio-Activity Profile
Antimicrobial Antifungal
Pseudomonas aeruginosa K799
4 μM
MIC
PaperNovel antimicrobial peptides derived from flatfish genes PMID12878506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878506/
RECORD: Rec_0350538 VERIFIED: YES
Provenance & Taxonomy
American plaice [Animal]; Actinopterygii [Animal]
33208; 7898
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID12878506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878506/
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