Peptide Database

Peptide NameNRC-12

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC135H208N38O31

DescriptionStandard

        GWKKWFNRAKKVGKTVGGLAVDHYL
    

Molecular Weight2859.33 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)4.84

Net Charge (pH 7.4) 4.58

Charge Density (pH 7.0) 0.1937

GRAVY Index-0.52

Hydrophobic Moment 0.72

Boman Index-0.02

Instability Index17.45

Aliphatic Index 74.00

Aromaticity 0.1600

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1134.83

LogP -7.10

H-bond Donors 41.0

H-bond Acceptors 37.0

Rotatable Bonds 95.0

Heavy Atoms 204.0

Ring Count 7.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0238105 VERIFIED: YES

Provenance & Taxonomy

OrganismHippoglossoides platessoides [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli DC2

Activity2 μg/mL

MethodMIC

RECORD: Rec_0247113 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Anticancer Antibacterial Toxic Antimicrobial Antifungal Hemolytic Anti-Gram-positive Anti-Gram-negative

RECORD: Rec_0252222 VERIFIED: YES

Provenance & Taxonomy

OrganismHippoglossoides platessoides [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetPseudomonas aeruginosa K799

Activity4 μg/mL

MethodMIC

RECORD: Rec_0263677 VERIFIED: YES

Provenance & Taxonomy

OrganismHippoglossoides platessoides [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetMRSA C623

Activity16 μg/mL

MethodMIC

RECORD: Rec_0301359 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

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