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MYP_021715
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Basic Information
PSPHa2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C96H153N23O24
Standard
Sequence
FLSLIPKAISAISALANHF
Physicochemical Analysis
2013.38 Da
8.76
0.85
0.59
0.0445
1.22
0.53
0.48
2.50
144.21
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
736.81
-4.58
25.0
26.0
63.0
143.0
4.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0272699 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0284586 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Phylloseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
U-251MG
36.46 μM
LD50
PaperPubMed PMID: 30774309 PMID30774309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30774309/
RECORD: Rec_0349055 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
8 μM
MIC
PMID30774309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30774309/
RECORD: Rec_0384652 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
horse erythrocytes
34.86 μM
HC50
PMID30774309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30774309/
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