Peptide Database

Peptide NameKlebicin B (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length288 amino acids

Chemical FormulaC1344H2149N375O418S9

DescriptionStandard

        MMPGDAFGLPDTAALNKAADQKTSVSMPVRGRLVMNDSGILDVQLVKTNTAGAVKVARAVLDKETGYWGYTLPAVADVPAQTIFVSTADALGANGPLTLSGPVPLPERILHTGDQISAPQATDKTVTPVADDLDFDDIILVFPPESGLKPLYVMYRSPRNMPGTVSGKGQNVGNNWMGGASTGDGAPVPSQIADKLRGKTFGSFDSSRRAFWKAVADDSALSKQFSEADINQMKAGRAPTADFLESVGKRVKIELHHEKEISQGGAVMDVDNIKALTPKNHIETHKGK
    

Molecular Weight30537.29 Da

Isoelectric Point (pI)6.22

Net Charge (pH 7.0)-2.04

Net Charge (pH 7.4) -2.57

Charge Density (pH 7.0) -0.0071

GRAVY Index-0.27

Hydrophobic Moment 0.63

Boman Index0.03

Instability Index38.81

Aliphatic Index 79.62

Aromaticity 0.0556

Extinction Coeff. Reduced 22460.00

Extinction Coeff. Oxidized 22460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0363955 VERIFIED: YES

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)