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MYP_021686
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Basic Information
Chensinin-1 (1-13) [A2K, G4,7,11W, L12H ]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C92H129N33O15
Standard
Sequence
SKVWRHWRRFWHR
Physicochemical Analysis
1937.22 Da
12.00
4.63
4.32
0.3564
-1.91
0.92
-0.61
77.58
22.31
0.3077
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
811.10
-3.61
33.0
22.0
59.0
140.0
9.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010745 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa CGMCC 1.860
3.13 μM
MIC
PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0042083 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis CGMCC 1.595
3.13 μM
MIC
PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0087840 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus AS1.72
3.13 μM
MIC
PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0098514 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperStructure-activity analysis and biological studies of chensinin-1b analogues. Acta Biomater. 2016 Jun;37:59-68. doi: 10.1016/j.actbio.2016.04.003. PMID: 27060618. PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0101135 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (- at NA
Hemolysis
PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
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