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MYP_021675
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Basic Information
P7
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
18 amino acids
C118H197N37O19
Standard
Sequence
WVRKVRRWWKKVKKVVKK
Physicochemical Analysis
2438.06 Da
12.00
9.75
9.54
0.5418
-1.25
1.00
-0.57
51.02
80.56
0.1667
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
973.23
-2.22
38.0
29.0
86.0
174.0
6.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011187 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
MRSA 18466
64 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0053292 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Murine blood [HC10 = 80.04 ± 7.2 microg/mL, HC50 = >640 microg/mL, Percent Hemolysis ± SD Hmax (100%) =25.54 ± 6.2]
640 μg/mL
HC50
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0162995 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Staphylococcus aureus ATCC 25923
64 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0189781 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Candida albicans ATCC 5314
64 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0218031 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
S. sangui ATCC 10556
64 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
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