Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC383H625N105O97S9

DescriptionStandard

        MKSLLLALVVLALLSCVPPVRSGPNMYIRRVFSTCWRSKGVCRKSCGKREEYHIFCDSAFLCCIDKKYLPIQIGK
    

Molecular Weight8541.29 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)8.52

Net Charge (pH 7.4) 8.13

Charge Density (pH 7.0) 0.1135

GRAVY Index0.26

Hydrophobic Moment 0.80

Boman Index0.04

Instability Index70.30

Aliphatic Index 100.00

Aromaticity 0.0933

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3237.48

LogP -24.63

H-bond Donors 123.0

H-bond Acceptors 116.0

Rotatable Bonds 283.0

Heavy Atoms 594.0

Ring Count 13.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0009099 VERIFIED: NO

Provenance & Taxonomy

OrganismZalophus californianus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

RECORD: Rec_0228488 VERIFIED: NO

Provenance & Taxonomy

OrganismCallorhinus ursinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence