Peptide Database

Peptide NameLEAP-2

Function Ontology

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Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC140H229N45O41S4

DescriptionStandard

        MTPFWRGVSLRPIGASCRDDSECITRLCR
    

Molecular Weight3326.85 Da

Isoelectric Point (pI)8.71

Net Charge (pH 7.0)1.48

Net Charge (pH 7.4) 1.21

Charge Density (pH 7.0) 0.0509

GRAVY Index-0.24

Hydrophobic Moment 0.64

Boman Index-0.16

Instability Index62.41

Aliphatic Index 67.24

Aromaticity 0.0690

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1398.88

LogP -15.51

H-bond Donors 55.0

H-bond Acceptors 47.0

Rotatable Bonds 106.0

Heavy Atoms 230.0

Ring Count 5.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0205643 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)