Peptide Database

Peptide NameNatriuretic peptide AsNP-a

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC138H233N43O46S3

DescriptionStandard

        SGSKTAKIGDGCFGVRIDRIGSTSGMGCGSVPKP
    

Molecular Weight3326.78 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)2.44

Net Charge (pH 7.4) 2.20

Charge Density (pH 7.0) 0.0718

GRAVY Index-0.18

Hydrophobic Moment 0.54

Boman Index0.03

Instability Index8.44

Aliphatic Index 54.41

Aromaticity 0.0294

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1424.11

LogP -21.63

H-bond Donors 53.0

H-bond Acceptors 52.0

Rotatable Bonds 111.0

Heavy Atoms 230.0

Ring Count 3.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0202887 VERIFIED: YES

Provenance & Taxonomy

OrganismAustrelaps superbus [Animal]

FamilyNatriuretic peptide AsNP

Tax ID29156

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-28

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour