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MYP_021618
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Tubulin-Tyrosine Ligase Inhibitor
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
2 amino acids
C12H16N2O4
Standard
Sequence
AY
Physicochemical Analysis
252.27 Da
5.57
-0.21
-0.39
-0.1026
0.25
0.31
0.44
5.00
50.00
0.5000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
112.65
-0.15
4.0
4.0
5.0
18.0
1.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0349461 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Tubulin-Tyrosine Ligase Inhibitor
PaperRaybin D., Flavin M.. Enzyme which specifically adds tyrosine to the alpha chain of tubulin. Biochemistry, 16, 2189-2194, 1977.
RECORD: Rec_0361583 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]
3847
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Spontaneously hypertensive rats (SHR)
48 μM
IC50
PaperAntihypertensive effect of peptide-enriched soy sauce-like seasoning and identification of its angiotensin I-converting enzyme inhibitory substances PMID19994857 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19994857/
RECORD: Rec_0375044 VERIFIED: NO
Provenance & Taxonomy
Zea mays [Plant]
ACE-inhibitory peptide
4577
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
9.5 mmHg
SBP decrease
PaperISOLATION AND CHARACTERIZATION OF PEPTIDES WITH ANTIHYPERTENSIVE ACTIVITY IN FOODSTUFFS. PMID24915368 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24915368/
RECORD: Rec_0396564 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]
3847
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Spontaneously hypertensive rats (SHR)
48 μg/mL
IC50
PaperAntihypertensive effect of peptide-enriched soy sauce-like seasoning and identification of its angiotensin I-converting enzyme inhibitory substances PMID19994857 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19994857/
RECORD: Rec_0410722 VERIFIED: NO
Provenance & Taxonomy
Fagopyrum esculentum [Plant]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
4-628 μM
IC50
PaperISOLATION AND CHARACTERIZATION OF PEPTIDES WITH ANTIHYPERTENSIVE ACTIVITY IN FOODSTUFFS. PMID24915368 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24915368/
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