Peptide Database

Peptide NameGramicidin A [l10,12,14k]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC96H138N22O16

DescriptionStandard

        VGALAVVVWKWKWKW
    

Molecular Weight1856.26 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)2.73

Net Charge (pH 7.4) 2.52

Charge Density (pH 7.0) 0.1821

GRAVY Index0.57

Hydrophobic Moment 0.27

Boman Index0.39

Instability Index-1.99

Aliphatic Index 116.67

Aromaticity 0.2667

Extinction Coeff. Reduced 22000.00

Extinction Coeff. Oxidized 22000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 611.94

LogP 2.81

H-bond Donors 23.0

H-bond Acceptors 19.0

Rotatable Bonds 55.0

Heavy Atoms 134.0

Ring Count 8.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0398440 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus ATCC 6538

Activity2.5-5 μM

MethodIC50

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