Peptide Database

Peptide NameColicin B activity protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length511 amino acids

Chemical FormulaC2426H3847N653O766S14

DescriptionStandard

        MSDNEGSVPTEGIDYGDTMVVWPSTGRIPGGDVKPGGSSGLAPSMPPGWGDYSPQGIALVQSVLFPGIIRRIILDKELEEGDWSGWSVSVHSPWGNEKVSAARTVLENGLRGGLPEPSRPAAVSFARLEPASGNEQKIIRLMVTQQLEQVTDIPASQLPAAGNNVPVKYRLTDLMQNGTQYMAIIGGIPMTVPVVDAVPVPDRSRPGTNIKDVYSAPVSPNLPDLVLSVGQMNTPVRSNPEIQEDGVTSETGNYVEAGYTMSSNNHDVIVRFPEGSGVSPLYISAVEILDSNSLSQRQEAENNAKDDFRVKKEQENDEKTVLTKTSEVIISVGDKVGEYLGDKYKALSREIAENINNFQGKTIRSYDDAMSSINKLMANPSLKINATDKEAIVNAWKAFNAEDMGNKFAALGKTFKAADYAIKANNIREKSIEGYQTGNWGPLMLEVESWVISGMASAVALSLFSLTLGSALIAFGLSSTVVGFVGVVIAGAIGAFIDDKFVDELNHKIIK
    

Molecular Weight54866.32 Da

Isoelectric Point (pI)4.82

Net Charge (pH 7.0)-17.15

Net Charge (pH 7.4) -17.66

Charge Density (pH 7.0) -0.0336

GRAVY Index-0.19

Hydrophobic Moment 0.67

Boman Index0.07

Instability Index40.48

Aliphatic Index 88.32

Aromaticity 0.0665

Extinction Coeff. Reduced 63370.00

Extinction Coeff. Oxidized 63370.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0287087 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyColicin/Pyocin

Tax ID562

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli

MethodQualitative functional evidence