Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC541H879N147O168S4

DescriptionStandard

        PDLTGHEKFALGNVKYNISRIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRGTVHISKVSVTAIFSTPLDDTDPMSISLTSCRTTSGDIDIKLNGKT
    

Molecular Weight12258.91 Da

Isoelectric Point (pI)8.46

Net Charge (pH 7.0)1.22

Net Charge (pH 7.4) 0.97

Charge Density (pH 7.0) 0.0107

GRAVY Index0.02

Hydrophobic Moment 0.54

Boman Index0.11

Instability Index22.69

Aliphatic Index 97.46

Aromaticity 0.0526

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5027.58

LogP -56.57

H-bond Donors 179.0

H-bond Acceptors 176.0

Rotatable Bonds 406.0

Heavy Atoms 860.0

Ring Count 16.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0376402 VERIFIED: NO

Provenance & Taxonomy

OrganismIrena cyanogastra [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria