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MYP_021535
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Basic Information
Protein GPR15LG (Protein GPR15 ligand) (Protein GPR15L)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Immunology ▸ Immune modulation ▸ Cytokine modulation
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
78 amino acids
C394H660N122O94S9
Standard
Sequence
MRLLALSGLLCMLLLCFCIFSSEGRRHPAKSLKLRRCCHLSPRSKLTTWKGNHTRPCRLCRNKLPVKSWVVPGALPQI
Physicochemical Analysis
8898.80 Da
10.93
13.69
13.21
0.1755
0.03
0.62
-0.05
60.72
100.00
0.0513
11000.00
11375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3450.99
-29.94
132.0
120.0
293.0
619.0
15.0
80.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001950 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Cytokine Anticancer Chemotactic Non-hemolytic
Mycoplasma (Gram-negative)
PaperLineage-specific biology revealed by a finished genome assembly of the mouse; A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15; A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia; C10orf99 contributes to the development of psoriasis by promoting the proliferation of keratinocytes; GPR15L is an epithelial inflammation-derived pruritogen PMID19468303;28936214;28900043;29872130;35704588 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19468303/
RECORD: Rec_0350060 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Cytokine Anticancer Chemotactic Non-hemolytic
Actinomyces (Gram-positive)
PaperLineage-specific biology revealed by a finished genome assembly of the mouse; A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15; A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia; C10orf99 contributes to the development of psoriasis by promoting the proliferation of keratinocytes; GPR15L is an epithelial inflammation-derived pruritogen PMID19468303;28936214;28900043;29872130;35704588 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19468303/
RECORD: Rec_0382053 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Cytokine Anticancer Chemotactic Non-hemolytic
Staphylococcus aureus (Gram-positive)
PaperLineage-specific biology revealed by a finished genome assembly of the mouse; A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15; A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia; C10orf99 contributes to the development of psoriasis by promoting the proliferation of keratinocytes; GPR15L is an epithelial inflammation-derived pruritogen PMID19468303;28936214;28900043;29872130;35704588 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19468303/