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MYP_021491
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Basic Information
Development regulating peptide
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Developmental biology ▸ Development regulation
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Neprilysin Inhibitor
Metabolic ▸ Uric acid metabolism ▸ Hypouricemic activity
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Regulatory peptide ▸ Biological regulation
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Standard
2 amino acids
C20H21N3O3
Standard
Sequence
FW
Physicochemical Analysis
351.40 Da
5.53
-0.24
-0.44
-0.1200
0.95
0.66
1.00
5.00
0.00
1.0000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
108.21
1.85
4.0
3.0
7.0
26.0
3.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0003419 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Regulatory
PaperTakahashi Y., Muneoka Y., Lohmann J., de Haro M. S. L., Solleder G., Bosch T. C. G., David C. N., Bode H. R., Koizumi O., Shimizu H., Hatta M., Fujisawa T., Sugiyama T.. Systematic isolation of peptide signal molecules regulating development in hydra: LWamide and PW families. Proc. Natl Acad. Sci. USA, 94, 1241-1246, 1997.
RECORD: Rec_0038931 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hypouricemic
PaperHe W., Su G., Sun-Waterhouse D., Waterhouse G. I., Zhao M., Liu Y.. In vivo anti-hyperuricemic and xanthine oxidase inhibitory properties of tuna protein hydrolysates and its isolated fractions. Food Chem., 272, 453-461, 2019.
RECORD: Rec_0055357 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae
80 μg/mL
MIC
PMID19081951 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19081951/
RECORD: Rec_0090206 VERIFIED: NO
Provenance & Taxonomy
Gallus gallus [Animal]
ACE-inhibitory peptide
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
3.9 μM
IC50
PaperQSAR-aided in silico approach in evaluation of food proteins as precursors of ACE inhibitory peptides
RECORD: Rec_0130906 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus
5 μg/mL
MIC
PMID19081951 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19081951/
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