Peptide Database

Peptide NameInterferon lambda-1

Function Ontology

Antiviral

Immunology ▸ Immune modulation ▸ Cytokine modulation

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length181 amino acids

Chemical FormulaC890H1433N259O256S5

DescriptionStandard

        GPVPTSKPTTTGKGCHIGRFKSLSPQELASFKKARDALEESLKLKNWSCSSPVFPGNWDLRLLQVRERPVALEAELALTLKVLEAAAGPALEDVLDQPLHTLHHILSQLQACIQPQPTAGPRPRGRLHHWLHRLQEAPKKESAGCLEASVTFNLFRLLTRDLKYVADGNLCLRTSTHPEST
    

Molecular Weight20017.81 Da

Isoelectric Point (pI)9.08

Net Charge (pH 7.0)5.44

Net Charge (pH 7.4) 4.71

Charge Density (pH 7.0) 0.0300

GRAVY Index-0.36

Hydrophobic Moment 0.83

Boman Index-0.04

Instability Index52.17

Aliphatic Index 90.61

Aromaticity 0.0497

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 18240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8189.76

LogP -95.43

H-bond Donors 286.0

H-bond Acceptors 274.0

Rotatable Bonds 654.0

Heavy Atoms 1410.0

Ring Count 35.0

Amide Bonds 192.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0181331 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Familylambda interferon family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide49-145

Bio-Activity Profile

Function

Cytokine Growth factor lambda interferon family Antiviral Host defense